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Therapy Boosts Lymphoma Cure Rate
More than half of laboratory mice with human non-Hodgkin’s lymphoma (NHL) are cured by a treatment involving just two monoclonal antibodies, researchers at the Stanford University School of Medicine have found. The therapy combines the activity of rituximab, an antibody currently in use to treat the disorder, with another that blocks a molecule called CD47 on the surface of the cancer cells. Together the two antibodies synergize to trigger the host’s own immune system to eliminate the cancer.
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NIH-sponsored Research Yields Promising Malaria Drug Candidate
A chemical that rid mice of malaria-causing parasites after a single oral dose may eventually become a new malaria drug if further tests in animals and people uphold the promise of early findings. The compound, NITD609, was developed by an international team of researchers including Elizabeth A. Winzeler, Ph.D., a grantee of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
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Functional Motor Neuron Subtypes Generated from Embryonic Stem Cells
Scientists have devised a method for coaxing mouse embryonic stem cells into forming a highly specific motor neuron subtype. The research, published by Cell Press in the September 3rd issue of the journal Cell Stem Cell, provides new insight into motor neuron differentiation and may prove useful for devising and testing future therapies for motor neuron diseases.
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Models Suggest Treatments for Fractures that Won't Heal
New models, reinforced by in vivo experimentation, show why 5-10% of bone fractures don't heal properly, and how these cases may be treated to restart the healing process. Results of the model, published September 2 in the open-access journal PLoS Computational Biology, may benefit the ageing population in which the occurrence of bone fractures is expected to rise substantially in the near future.
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Coaching to Improve Employee Performance
Coaching often provides positive feedback about employee contributions. At the same time, regular coaching brings performance issues to an employee's attention when they are minor, and assists the employee to correct them.
The goal of coaching is to work with the employee to solve performance problems and improve the work of the employee, the team, and the department.
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